View Full Version : Domperidone

05-25-2006, 08:52 PM
I have started taking Domperidone to get my milk supply back. I lost it at about 3 months Postpartum due to hypothyroidism, which has since been corrected.

I am taking 20 mg, 3x/day. I just started it last night.

For any ladies who have used Domperidone (I tried 1 liter of Mothers Milk tea and 12 fenugreek pills and it didnt work), how long did it take for your milk to come back, and did you get back to your full supply?

Currently, I get an ounce and a half pumping during the day, half an ounce pumping at night, and about 2 ounces nursing in the morning. I have been consistantly trying to nurse and pumping 3-4 times daily since my baby was 6 weeks, even with the lack of supply.

05-25-2006, 09:04 PM
I stopped bfing my son at a little after 2 weeks due to some severe post partum issues, LOL. That and I just couldn't take the pain of nursing anymore. I took fenugreek and all that good stuff, but never tried the tea because I didn't want to order online back then. Anyway... after what seemed like forever I tried the Domperidone. I think at the most after I started taking it I got an ounce (both breasts together). BUT I was completely dried up, sounds like you're doing just fine. There's the possibility that you MAY get a full supply back. I don't know that they guarantee it, and I wouldn't either. It depends mostly on how well your body reacts to the medication, etc. I stopped after a few weeks of pumping for what seemed like forever. I couldn't take it anymore, LOL, but you are far ahead of what I was making in the first place! Good luck with it! It was the only thing that started my supply back up in the first place, so you may have GREAT results on it. Oh, as for how long it took for my milk to come back it was maybe between 1-2 weeks to notice much of a change. I noticed little changes within the first few days, but nothing spectacular until a little later. BTW, it did make me gain over 10 lbs. though, LOL, if you're concerned about that. I wasn't, though - milk seems so much more important than weight!

05-25-2006, 09:44 PM
I used domp to induce lactation for my adoptive dd. Within 2 days, I had a streams and within 2 weeks I had enough to bf her without use of lact-aid. So, my story is different than yours but to show that I use domp and was able to soley bf within 2 weeks. I never pumped.

Good luck:goodvibes:

05-26-2006, 05:28 PM
how safe is this I am getting a box sent to me by a friend because my supply is almost gone and i want to start breastfeeding my again.

05-26-2006, 05:42 PM
how safe is this I am getting a box sent to me by a friend because my supply is almost gone and i want to start breastfeeding my again.

05-26-2006, 07:45 PM
How are you getting a box sent by a friend...you have to have a prescription for it? Like any drug, there are side effects. Domperidone is actually used to treat stomach problems, increased lactation is just a side effect. You really need to discuss it with your doctor before using it (or any drug) because your own medical history may affect how your body responds. In the US, the FDA has issued a warning against Domperidone and it is illegal for pharmacies to dispense it. The warning is controversial for several reasons, but it is something to consider and discuss with your physician. There are other options for increasing your milk supply or "relactation" as well.

Here's some info about Domperidone (good and bad):

General info on relactating:

Good luck with whatever you decide to do... :)

05-26-2006, 07:59 PM
she had ordered a box online I wasnt going to use it till i talk to my dr. She is also sending me fenugreek and mothers milk tea. which is the route i will be taking now i am just looking for someone to send me some blessed thistle.

05-26-2006, 08:15 PM
I discussed it with a doctor, who informed me he was not allowed to prescribe it.

After a lot of research, I was able to determine that one of the main reasons it is not prescribed for milk production is because formula is so easy and accessible in the US - who's gonna sponsor a product that no one needs?

At any rate, the side effects (The really negative ones) are sited as being caused by human-sized dosages in rats. By human sized, I mean like 90mg/day. They used to give it to infants in much smaller doses for reflux - now it's only available overseas to treat adult reflux.

I have not yet had any side effects - and today pumped 4oz in three sittings and had one full nursing. So far, it is working for me! I hope this continues.

But I had to order mine from New Zealand. It's brand-name, cost me $30ppd for 100 10mg pills.

05-26-2006, 08:36 PM
I discussed it with a doctor, who informed me he was not allowed to prescribe it.

After a lot of research, I was able to determine that one of the main reasons it is not prescribed for milk production is because formula is so easy and accessible in the US - who's gonna sponsor a product that no one needs?

Based on what I've read, I do think that the FDA was hasty in banning it, but I don't think the "formula conspiracy" had much to do with this one. Even in Canada, where it is legal, it is not "approved" for milk production. That is a very common "off-label" use for it, but neither the drug company nor the government officially endorses it for that (meaning also that they haven't tested the long term effects on mothers or babies...). It is approved for use in treating stomach problems. It was the same in the US...it was approved for treating stomach problems here and that's what the FDA considered when they pulled it. As for who's going to "sponsor" a product that no one needs...since when has that ever stopped a drug company? They're the ones that run the healthcare industry in this country! :D

By the way, even though Domperidone is not legal in the US, reglan is and is frequently prescribed for increasing milk production here. It does have more side effects in some women but it's something to consider and discuss with your doc. And here are some more that are available without a prescription (you should be able to get them at most any herb store) http://www.drjaygordon.com/development/bf/galact.asp

One last thing to think about when ordering drugs online or especially getting them through a friend, if you get caught, it's drug trafficking. They let cocaine and heroin dealers off with nothing but you can bet they'd try to make an example out of a suburban mom over something like this! The chances of getting caught are slim, but you do need to think about it.

I know it's a tough position to be in. My son was unable to latch at birth so I wound up exclusively pumping for the first 7 weeks...trying to establish and maintain your supply when you're not nursing at all is killer. I did it, but I wound up having oversupply issues. By the time he started nursing, I was already back at work full time so I had to try to decrease my supply while only being able to nurse about 50% of the time. That led to a yo-yo effect that was a nightmare. Even once things leveled out, I had a really hard time maintaining an adequate supply when things were hectic at work or he was going through a growth spurt or whatever. I did stick it out though and he weaned himself at 19 months (only because I was 4 months pregnant again). Through all the trials, I am so glad that I stuck with it. Good luck to all of you, I hope that you are able to work things out as well.

05-26-2006, 09:17 PM
I have gastroparesis (the stomach ailment it treats) and while it's under control right now, if I need it my US doctor will prescribe me doperidone. It is not illegal in the US, many pharmacies will formulate it for you.

I discussed it in length with my gastroenterologist and he told me that the drug company spent millions on getting approved. Once the trials were complete the FDA asked for different trials because apparently there was a misunderstanding during the original application. Well, because the drug had already cost them millions they did not feel that it was worth it to go through it again so they chose to not have it in the US market.

No danger, no issues. Just financial issues surrounding the approval. Here is a list of pharmacies in the US that will fill it;


05-26-2006, 09:33 PM
unfortunatly not MA where I am from

05-26-2006, 10:01 PM
I have gastroparesis (the stomach ailment it treats) and while it's under control right now, if I need it my US doctor will prescribe me doperidone. It is not illegal in the US, many pharmacies will formulate it for you.

It may be true that many pharmacies will formulate it for you, but many pharmacies (including several from the list on the link you provided) have been issued warning letters by the FDA. This is from the FDA website: http://www.fda.gov/bbs/topics/ANSWERS/2004/ANS01292.html

The letters issued by FDA today stated that all drug products containing domperidone (whether compounded or not) violate the Federal Food, Drug, and Cosmetic Act (the Act) because they are unapproved new drugs and misbranded. In addition, distribution within the U.S., or importation of domperidone-containing products, violates the law. FDA informed the warning letter recipients that further violations of the Act may result in enforcement actions including seizure and injunction.

Like you, I also read that it was a marketing decision by the drug manufacturer not to pursue FDA approval. I also read that there are risks associated with the drug (duh...there are risks associated with all drugs!) Even in Canada, apparently it comes with a warning that it should not be used by breastfeeding mothers because it is unknown how it will affect the nursing baby. Personally, I wish that they would do the testing and research necessary to get it labelled and approved for increasing milk supply all over the world. They know that a significant number of people are using it for that already. In fact, maybe I just don't know too many people with gastroparesis (?) but I would venture a guess that more people use it for lactation than for what it's labelled for! Still, as much as I wish they would approve it for use here in the US, they haven't, so if someone is thinking of using it, they need to consider that.

05-26-2006, 10:17 PM
Man that blows because I ried the alternate drug Reglan and it is evil!! It made me so anxiety ridden that I felt like tearing off my skin. One of its known and common side effects is auditory hallucinations! I couldn't take it even for two days. When I am pregnant the condition is exacerbated so that I vomit up every dinner. Reglan really worked but the side effects were far worse than the puking so I went off of it. My only hope for a decent pregnancy was the doperidone...:cry:

If it comes down to it, I'll break the law. I asked DH about it (he's an asst district attorney) he said with a non-narcotic it's a misdemeanor and he doubts that anyone would ever be caught much less charged.

It makes me sad to think that someones only shot at nursing is a crime. :headscratch:


05-26-2006, 11:02 PM
Yuck! I've heard that Reglan has some pretty nasty side effects! The breastfeeding board I've been going to for the past two years is in Canada and half the women on there have used Domperidone. I was just talking to one of the PAs in my doc's office who happened to be nursing one day and the subject came up. She told me that they usually use Reglan here instead of Domperidone but she didn't elaborate. When I went to look up side effects for the other poster, that's the first I'd heard that it was illegal here! It does suck...I so wish they would do the necessary steps to get it labelled for lactation...for pete's sake this is a drug company! Do they not realize what a huge market there would be if they would just make the investment? And the FDA? They're plenty quick to approve other drugs without much research (Viagra, those arthritis drugs I can't think of the name of right now), why not one that could actually help so many people? Maybe the formula conspiracy does have something to do with it after all! ;)

05-26-2006, 11:13 PM
that was kinda funny formula conspiracy yep maybe

05-26-2006, 11:27 PM
I know that a lot of moms have given you a lot of great advice. But being that milk supply, or lack there of hits home to me, I felt the need to share. I am proudly beginning my 7 month mark of almost exclusively BF'ding my DS. I am a breast reduction mommy and was not sure if I was even going to be able to nurse at all. With my first son I was uneducated as to how I could increase my supply, so unfortunatly I only bf'd him for 12 weeks. This time I was sure to find out ALL of my options. I have used DPD.. I orded it online from outsite of the country. I felt personally that it was better then reglan, which did nothing for me. THe only problem is that eventually it got stopped at the border and I didnt want to take that chance again. SO I ended up going with an herbal route that acutally worked better for me then DPD in the long run. Of course I take fenugreek, 3 caps, 3x's a day. But I also have added Blessed Thistle(same dosage as Fenugreek) and to top it off I take a tincture of Goats rue 3'xs a day too. I know it seems like a lot but lemme tell ya! It has worked miracles. I am able to make up 3/4 of what my baby needs everday which is no small thing for a mom post breast reduction. So I would highly recommend the herbal route.. its easier to get ahold of here in the states and natural, which is always a plus! Sorry this is so long, I just know whats its like to need to increase my supply and this is what worked for me. Good luck!!! Oh and on a side note.. with the DPD.. I felt an increase about 2 weeks into taking it.. like my milk had come in for a second time!

05-27-2006, 08:11 AM
Unfortuantely, that list of pharmacies needs to be updated - I called all within 200 miles of me and had no luck.

I have had no side effects from the DPD, and was able to exclusively feed DD her breakfast. It is worth it to me. Also, they code the shipment overseas as "dietary supplements" so that customs will not seize it.

It technically IS illegal - and ordering it from overseas has been great for me, and I will continue to do so! :)

05-27-2006, 09:50 AM
All I have heard is good from this drug. I only get about 3 drops of milk from each breast right now and I really really want to nurse my daughter again. I have no allergies to medications and I am way way to healthy.

05-27-2006, 11:44 AM
www.globaldrug.tv is where I got mine from. $30 for 100 10mg pills with shipping - got them in 2 weeks.

05-31-2006, 01:24 PM
My milk got as low as 1/2 ounce every time I pumped, sometimes less. Now, after a week and a half on the Domperidon, I had seen only a little increase - up to 2 ounces per pump. So I increased my dosage, 30mg 3x/day, since I had only been taking 20mg 3x/day, and I woke up engorged as crazy today, and nursed my baby, then pumped 4 ounces and then another 2 ounces. I suspect I will get another 2 ounces this afternoon, and then be able to nurse her again - so I'll have enough to send 2 full bottles of breastmilk to daycare daily.

I am SO thrilled that my baby girl now gets more breastmilk than formula. She was getting MAYBE one full serving of breastmilk per day - and now she'll be getting only one to two bottles of formula per day. Hooray!!!